Gut bacteria blocks GLP-1
Link to article in Reddit.
I asked Copilot: why does Desulfovibrio species intervene?
Answer: Desulfovibrio species intervene in metabolism by producing hydrogen sulfide, a cytotoxic compound that directly disrupts GLP-1 hormone production. GLP-1 plays a key role in regulating satiety and metabolic efficiency. By interfering with its synthesis, Desulfovibrio species create a cascade of metabolic dysfunction:
Impaired appetite regulation – With GLP-1 suppressed, the body struggles to signal fullness, leading to increased food intake.
Heightened inflammation – This affects receptor sensitivity, making metabolic regulation more difficult.
Compromised gut barrier – Hydrogen sulfide weakens intestinal integrity, allowing harmful substances to enter the bloodstream.
Essentially, these bacteria function as metabolic disruptors, counteracting both natural and pharmaceutical interventions for weight management. Their presence in the gut microbiome explains why some individuals face resistance to diet or medication-based strategies.
My Conclusion:The 'money shot': GLP-1 plays a key role in regulating satiety...
Satiety: "the state or feeling of being completely full of food, or of having had enough of something."
A simple solution: expensively made chocolate.
